PathwayScan™ Multi-Pathway Reporter Kit

• Looking for novel signaling pathways in which a gene is involved
• Identifying signaling pathways influenced by a mutant gene, microRNA, siRNA, or shRNA
• Studying crosstalk of signal pathways
• Identifying signaling pathways influenced by various stimuli (cytokines, chemokines, chemicals, hormones, etc.)
• Signaling pathway profiling in a variety of scenarios
• Screening signaling pathways influenced by home-made cells (transient or stable, overexpressed or knock-down, knock-out or knock-in)
• Identifying the phenotype of transgenic, knock-out or knock-in mice
• Drug screening

Benefits

• Detects both activation and inhibition of transcription factors—a huge benefit rarely achieved by other methods.
• Simultaneously screens 46 different signaling pathways relevant to cancer, immunology, stem cells, etc.
• A single experiment can lead to many new discoveries (see data below).